Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma

Summary

This phase I trial studies the side effects and best dose of ascorbic acid when given together with bevacizumab in treating patients with high grade glioma that has come back (recurrent). Monoclonal antibodies, such as bevacizumab may interfere with the ability of tumor cells to grow and spread. Ascorbic acid contains ingredients that may prevent or slow the growth of high grade glioma. Giving bevacizumab and ascorbic acid together may work better in treating patients with high grade glioma.

Timeline

Start

2016-03

Primary completion

2019-03

Completion

2019-03

Drugs

Indications