drugset / Trial / NCT02834507
Effect of Two Multiple-dose Regimens of BIA 3-202 on the Pharmacokinetics and Motor Response of Levodopa, and on the Erythrocyte Comt Activity in Parkinson's Disease Patients
RandomizedCrossoverDouble-blindTreatment
Summary
The purpose of this study is to determine the effect of two different multiple-dose regimens of nebicapone in comparison to placebo and entacapone 200 mg on the pharmacokinetics of levodopa in Parkinson's Disease (PD) patients.
Timeline
- Start
- 2005-03
- Primary completion
- 2005-11
- Completion
- 2005-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Entacapone | Small molecule | 200 mg | — |
| Subject | Nebicapone | Small molecule | 75 mg | — |
| Subject | Nebicapone | Small molecule | 150 mg | — |
| Background | Levodopa | Small molecule | — | — |