drugset / Trial / NCT02834780

Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of H3B-6527 in Participants With Advanced Hepatocellular Carcinoma

NCT02834780 ↗

Phase 1 Completed 128 enrolled H3 Biomedicine Inc. Eisai Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of H3B-6527, and to assess the safety, tolerability and pharmacokinetics of H3B-6527.

Timeline

Start
2016-12-28
Primary completion
2022-02-23
Completion
2022-02-23

Drugs

EvaluationDrugModalityDoseRoute
Subject H3B-6527 Small molecule — Oral