drugset / Trial / NCT02835729

A Study of Indoximod in Combination With (7+3) Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia

NCT02835729

Phase 1 Completed 54 enrolled NewLink Genetics Corporation
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to characterize the regimen limiting toxicities (RLT) and recommended Phase 2 dose (RP2D) of indoximod in patients with newly diagnosed AML receiving remission induction chemotherapy with cytarabine and idarubicin.

Timeline

Start
2016-07
Primary completion
2019-10-25
Completion
2019-12-27

Drugs

EvaluationDrugModalityDoseRoute
Subject Indoximod Small molecule
Background Cytarabine Small molecule
Background Idarubicin Small molecule