drugset / Trial / NCT02836171

Effect of Itraconazole on the Pharmacokinetics of Apatinib

NCT02836171

Phase 1 Completed 20 enrolled Jiangsu HengRui Medicine Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

he primary purpose of this study is to investigate potential pharmacokinetic interaction in healthy volunteers when apatinib is administered in combination with itraconazole. Secondary objective is evaluating the safety and tolerability of apatinib alone and when co-administered with itraconazole.

Timeline

Start
2016-07
Primary completion
2017-02
Completion
2017-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Itraconazole Small molecule 100 mg Oral
Subject Rivoceranib Small molecule 250 mg Oral

Indications