drugset / Trial / NCT02836171
Effect of Itraconazole on the Pharmacokinetics of Apatinib
NaSingle-groupOpen-labelTreatment
Summary
he primary purpose of this study is to investigate potential pharmacokinetic interaction in healthy volunteers when apatinib is administered in combination with itraconazole. Secondary objective is evaluating the safety and tolerability of apatinib alone and when co-administered with itraconazole.
Timeline
- Start
- 2016-07
- Primary completion
- 2017-02
- Completion
- 2017-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | 100 mg | Oral |
| Subject | Rivoceranib | Small molecule | 250 mg | Oral |