drugset / Trial / NCT02836821
Effect of Rifampicin on the Pharmacokinetics of Apatinib
NaSingle-groupOpen-labelTreatment
Summary
The primary purpose of this study is to investigate potential pharmacokinetic interaction in healthy volunteers when apatinib is administered in combination with rifampicin. Secondary objective is evaluating the safety and tolerability of apatinib alone and when co-administered with rifampicin.
Timeline
- Start
- 2016-05
- Primary completion
- 2017-02
- Completion
- 2017-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rifampin | Small molecule | 600 mg | Oral |
| Subject | Rivoceranib | Small molecule | 750 mg | Oral |