drugset / Trial / NCT02837978
The Efficacy and Safety of Tacrolimus in Refractory Rheumatoid Arthritis Patients for 6 Months and Long-term Treatment
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This study is designed to observed prospectively the efficacy and safety of 6 months and long-term treatment of Tacrolimus alone or with methotrexate (MTX) in moderate and severe Chinese RA patients who shown insufficiency response or intolerance to DMARDs
Timeline
- Start
- 2015-01
- Primary completion
- 2022-09-30
- Completion
- 2022-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | MTX | Unknown | 5 mg | Oral |
| Comparator | MTX | Unknown | 15 mg | Oral |
| Subject | Tacrolimus | Small molecule | 0.5 mg | Oral |
| Subject | Tacrolimus | Small molecule | 1 mg | Oral |