drugset / Trial / NCT02838576

Effects of Hormone Replacement Therapy on Arthralgia in Postmenopausal Women

NCT02838576

Phase 2 Unknown 72 enrolled Hospital de Clinicas de Porto Alegre
RandomizedParallel-groupDouble-blindTreatment

Summary

Arthralgia has been a common complaint in postmenopausal period which seems to be involved with estrogen depletion, although, its pathophysiology isn´t completely clarified. It seems to relate with the level of physical activity, climacteric symptoms and pain catastrophizing. In view of the multiple dimensions involved in arthralgia in postmenopausal women which characterize it as a complex phenomenon, this study aims to describe the effects of hormone replacement therapy in women aged between 45 and 55 years, considering estrogen as a possible anti-nociceptive factor.

Timeline

Start
2017-03-01
Primary completion
2019-12-02
Completion
2020-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject conjugated estrogens Other / unclassified 0.625 mg Oral

Indications