drugset / Trial / NCT02841774

High Intensity Lipid Lowering Following Acute Coronary Syndromes for Persons Living With HIV

NCT02841774

Phase 2 Completed 10 enrolled Matthew Feinstein
RandomizedParallel-groupOpen-labelTreatment

Summary

HILLCLIMBER is a randomized, controlled, open-label phase II trial of moderate dose statin therapy (pravastatin 40mg daily) versus high-dose statin therapy (rosuvastatin 20-40mg daily) in HIV-infected persons taking antiretroviral therapy (ART) who have coronary heart disease (CHD).

Timeline

Start
2016-11
Primary completion
2021-06
Completion
2021-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pravastatin Small molecule 40 mg
Subject Rosuvastatin Small molecule 20 mg
Subject Rosuvastatin Small molecule 40 mg