drugset

drugset / Trial / NCT02844673

Mobile-Directly Observed Therapy on Adherence to Hydroxyurea

NCT02844673 ↗

Phase 2 Completed 98 enrolled Muhimbili University of Health and Allied Sciences Muhimbili National Hospital · collab University of Pittsburgh · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

To examine the effect of mobile-directly observed therapy (mDOT) on adherence to HU (mDOT-HuA) adults with SCA at Muhimbili National Hospital (MNH) in Tanzania.

Timeline

Start: 2017-04-28
Primary completion: 2018-01-28
Completion: 2018-05-18

Publications

Makubi A, Sasi P, Ngaeje M, Novelli EM, Mmbando BP, Gladwin MT, Makani J. Rationale and design of mDOT-HuA study: a randomized trial to assess the effect of mobile-directly observed therapy on adherence to hydroxyurea in adults with sickle cell anemia in Tanzania. BMC Med Res Methodol. 2016 Oct 18;16(1):140. doi: 10.1186/s12874-016-0245-9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Hydroxyurea	Other / unclassified	15 mg/kg	—

Indications