drugset / Trial / NCT02845414
Study of CD133KDEL Toxin in the Treatment for Solid Tumors
NaSingle-groupOpen-labelTreatment
Summary
This is a single center, phase I dose escalation study designed to determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D) of deimmunized CD133KDEL (dCD133KDEL), a ligand-directed, deimmunized pseudomonas toxin against CD133, in patients with advanced, previously treated, refractory solid tumors.
Timeline
- Start
- 2018-12
- Primary completion
- 2022-01
- Completion
- 2022-01
Outcome
Outcome not reported
Stopped (Business): “Funding unavailable”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CD133KDEL | Protein / enzyme biologic | — | Intravenous |