The Efficacy of G-CSF Against Adhesion Reformation After Hysteroscopic Adhesiolysis

Unknown 240 enrolled Sir Run Run Shaw Hospital Ningbo Women & Children's Hospital · collab Wenzhou people's hospital，zhejiang province,China · collab

RandomizedParallel-groupDouble-blindPrevention

Summary

The purpose of this study is to investigate the efficacy of Granulocyte Colony Stimulating Factor(G-CSF) on decreasing adhesion reformation and improving fertility outcomes after hysteroscopic adhesiolysis in patients with moderate to severe intrauterine adhesions.

Timeline

Start: 2016-08
Primary completion: 2018-12
Completion: 2019-12

Publications

Zhang Y, Chen X, Chen S, Wei C, Li B, Wang Z, Shen X, Lin X. Intrauterine administration of G-CSF for promoting endometrial growth after hysteroscopic adhesiolysis: a randomized controlled trial. Hum Reprod. 2022 Apr 1;37(4):725-733. doi: 10.1093/humrep/deac023.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	G-CSF	Unknown	300 ug	Other
Background	estradiol valerate	Unknown	6 mg	—
Background	medroxyprogesterone acetate	Other / unclassified	6 mg	—

The Efficacy of G-CSF Against Adhesion Reformation After Hysteroscopic Adhesiolysis

Summary

Timeline

Publications

Drugs

Indications