drugset / Trial / NCT02863575
A Dental Pain Study Comparing The Analgesic Efficacy Of Ibuprofen/Caffeine
RandomizedParallel-groupTriple-blindTreatment
Summary
An efficacy study assessing analgesic effect of ibuprofen/caffeine in post-surgical dental pain.
Timeline
- Start
- 2017-10-24
- Primary completion
- 2018-04-06
- Completion
- 2018-04-06
Outcome
Missed primary endpoint
registry analysis (superiority test); Ibuprofen 400 mg + Caffeine 100 mg vs Ibuprofen 400 mg; p = 0.306; Least square (LS) means difference 2.68 (95% CI -2.46 to 7.82); ANCOVA NCT02863575 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Caffeine | Small molecule | 100 mg | Oral |
| Comparator | Ibuprofen | Small molecule | 400 mg | Oral |
Indications
No indication recorded.