Is an Antiplaque Chewing Gum (30 mg) Able to Reduce Dental Plaque in a Healthy Population?

Summary

The Safety, efficacy and tolerability of an Antimicrobial Chewing Gum Formulation in Reducing Dental Plaque

Timeline

Start

2016-10

Primary completion

2016-11

Completion

2016-11

Outcome

Met primary endpoint

paper The APCG significantly inhibited the regrowth of dental plaque over the course of 4 days. PMID 32558314 ↗

paper with a two-tailed P value of .0003. PMID 32558314 ↗

Publications

• Kirkwood B, Miller M, Milleman J, Milleman K, Leung K. Four-day plaque regrowth evaluation of a peptide chewing gum in a double-blind randomized clinical trial. Clin Exp Dent Res. 2020 Jun;6(3):318-327. doi: 10.1002/cre2.275. Epub 2019 Dec 14.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Antimicrobial decapeptide KSL-W	Peptide	30 mg	—

Indications

No indication recorded.