drugset / Trial / NCT02875743

King's Invasive Aspergillosis Study II

NCT02875743

Phase 4 Completed 120 enrolled King's College Hospital NHS Trust
NaSingle-groupOpen-labelPrevention

Summary

Invasive fungal disease (IFD) is an important cause of mortality and morbidity in patients undergoing intensive chemotherapy or transplantation. This current study aims to assess the impact of prophylactically using the broad-spectrum anti-fungal agent posaconazole on the incidence of IFD in high risk patients with aplastic anaemia and those undergoing intensive chemotherapy, for example for acute myeloid leukaemia, and allogeneic stem cell transplantation.

Timeline

Start
2016-12-07
Primary completion
2018-10-31
Completion
2019-10-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Posaconazole Small molecule