drugset / Trial / NCT02876861
Neoadjuvant Chemotherapy Versus Surgery Alone in Patients With High-Grade UTUC
Phase 2
Completed
74 enrolled
Xiangya Hospital of Central South University
Central South University · collabHunan Cancer Hospital · collabHunan Provincial People's Hospital · collabThe Third Xiangya Hospital of Central South University · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to see if getting chemotherapy with Gemcitabine and Cisplatin (GC) for 2-4 cycles can help shrink the tumor before undergoing surgery and improves the overall survival for high-grade upper tract urothelial carcinoma.
Timeline
- Start
- 2014-02
- Primary completion
- 2022-08
- Completion
- 2022-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cisplatin | Other / unclassified | 75 mg/m2 | — |
| Subject | Gemcitabine | Small molecule | 1250 mg/m2 | — |