HexafluOride, a Contrast Agent for Placenta Echo-angiography

Summary

The purpose of this study is to quantify the placental perfusion during the first trimester of pregnancy by 3D Doppler ultrasound angiography without a contrast agent and by ultrasound with a contrast agent: SonoVue®

Timeline

Start

2016-10-12

Primary completion

2019-09-30

Completion

2019-09-30

Publications

• Results Bertholdt C, Morel O, Hossu G, Cherifi A, Beaumont M, Eszto ML. Evaluation of utero-placental vascularization using contrast-enhanced ultrasound: Early first trimester maternal perfusion of the intervillous space is confirmed. Placenta. 2024 Mar 25;148:53-58. doi: 10.1016/j.placenta.2024.02.004. Epub 2024 Feb 13.
• Bertholdt C, Eszto ML, Tournier M, Hossu G, Mellouki N, Cherifi A, Morel O. Assessment of uteroplacental vascularisation in early first-trimester pregnancy with contrast-enhanced ultrasound and 3D power Doppler angiography: protocol for a prospective, cross-sectional, multicentre and non-randomised open study ("HOPE Study"). BMJ Open. 2019 Sep 11;9(9):e030353. doi: 10.1136/bmjopen-2019-030353.

Drugs

Indications