drugset / Trial / NCT02885597
Juanbi Pill for Rheumatoid Arthritis
Phase 2/3
Unknown
120 enrolled
Cui xuejun
Longhua Hospital · collabShanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine · collabShanghai Yueyang Integrated Medicine Hospital · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to determine whether Juanbi Pill combined with methotrexate are effective in the treatment of active Rheumatoid Arthritis (RA).
Timeline
- Start
- 2018-07
- Primary completion
- 2018-12
- Completion
- 2020-12
Publications
- Jia QY, Wang YR, Sun DW, Mao JC, Xue L, Gu XH, Yu X, Piao XM, Xu H, Liang QQ. Efficacy and Safety of Juan Bi Pill with Add-on Methotrexate in Active Rheumatoid Arthritis: A 48-Week, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial. Chin J Integr Med. 2025 Feb;31(2):99-107. doi: 10.1007/s11655-024-3768-7. Epub 2024 Dec 21.
- Wang Q, Wang YR, Jia QY, Liu L, Xu CQ, Wang XY, Yao M, Cui XJ, Shi Q, Wang YJ, Liang QQ. The efficacy of the traditional Chinese medicine Juanbi pill combined with methotrexate in active rheumatoid arthritis: study protocol for a randomized controlled trial. Trials. 2018 Mar 20;19(1):188. doi: 10.1186/s13063-018-2555-1.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Juanbi pill | Traditional medicine (herbal / TCM) | 4 g | Oral |
| Background | Methotrexate | Small molecule | 5 mg | Oral |