drugset / Trial / NCT02885974

Celecoxib With Chemotherapy in Localized, Muscle-Invasive Bladder Cancer

NCT02885974

Phase 1 Completed 22 enrolled Baylor College of Medicine
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to compare patient tumor tissue before and after treatment with chemotherapy plus celecoxib. Investigators will look at gene expression, to see what effect celecoxib may have on tumor cells.

Timeline

Start
2016-12
Primary completion
2024-03
Completion
2025-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Celecoxib Other / unclassified 100 mg
Subject Cisplatin Other / unclassified 70 mg/m2 Intravenous
Subject Gemcitabine Small molecule 1000 mg/m2 Intravenous