drugset / Trial / NCT02895529
A Study Comparing the Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Participants With Hematological Malignancy
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to investigate the hypothesis that the efficacy of intravenous (IV) itraconazole followed by oral itraconazole is non-inferior to that of intravenous caspofungin as empiric therapy for suspected fungal infection participants with fever and neutropenia.
Timeline
- Start
- 2016-11-30
- Primary completion
- 2018-05-02
- Completion
- 2018-05-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Caspofungin | Other / unclassified | 50 mg | Intravenous |
| Subject | Itraconazole | Small molecule | 200 mg | Intravenous |