drugset / Trial / NCT02896400
Optimizing Tobacco Dependence Treatment in the Emergency Department
Phase 3
Completed
1056 enrolled
Yale University
National Cancer Institute (NCI) · collabNational Institutes of Health (NIH) · collab
RandomizedFactorialSingle-blindTreatment
Summary
The investigators propose an innovative full-factorial design in a cohort of 1056 adult smokers in an urban emergency department (ED), to test the efficacy of four key intervention components: motivational interviewing, medication, quitline referral, and texting. At the trial's completion, a mixed-methods approach will be used to identify the components that were efficacious within the proposed cost constraint, along with feasibility and acceptability to providers and subjects. The investigators will then assemble an intervention that maximizes efficacy, given a cost-effectiveness constraint and findings from a qualitative analysis.
Timeline
- Start
- 2017-02-13
- Primary completion
- 2019-08-14
- Completion
- 2019-08-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nicotine | Unknown | 2 mg | — |
| Subject | Nicotine | Unknown | 14 mg | — |
| Subject | Nicotine | Unknown | 21 mg | — |