Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention

Phase 2 Completed 118 enrolled The University of Texas Health Science Center, Houston

RandomizedParallel-groupQuadruple-blindTreatment

Summary

First, the investigators will determine whether Acceptance and Commitment Therapy in combination with Contingency Management increases initial treatment response rates. Second, for patients who do not respond to initial treatment, the investigators will examine whether dopamine-targeted pharmacotherapy is an effective augmentation strategy. Third, for patients who respond to initial treatment, the investigators will assess the relative benefit of continued treatment with Acceptance and Commitment Therapy in combination with Contingency Management, as compared to Drug Counseling in combination with Contingency Management, to prevent relapse.

Timeline

Start: 2016-11-18
Primary completion: 2021-09-13
Completion: 2021-09-13

Publications

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Modafinil	Small molecule	300 mg	—

Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention

Summary

Timeline

Publications

Drugs

Indications