drugset / Trial / NCT02899988
A Study of Mirikizumab (LY3074828) in Participants With Moderate to Severe Plaque Psoriasis
RandomizedParallel-groupDouble-blindTreatment
Summary
The main purpose of this study is to evaluate the efficacy of the study drug mirikizumab in participants with moderate to severe plaque psoriasis.
Timeline
- Start
- 2016-09-14
- Primary completion
- 2017-06-19
- Completion
- 2019-05-08
Outcome
Met primary endpoint
registry analysis (superiority test); Induction: Placebo vs Induction: 30 mg Mirikizumab; p = 0.009; Risk Difference (RD) 29.4 (95% CI 16.9 to 41.9); Regression, Logistic NCT02899988 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mirikizumab | Monoclonal antibody | 30 mg | Subcutaneous |
| Subject | Mirikizumab | Monoclonal antibody | 100 mg | Subcutaneous |
| Subject | Mirikizumab | Monoclonal antibody | 300 mg | Subcutaneous |