drugset / Trial / NCT02902016
Modulation of Lactase Expression by a New PPARgamma Ligand in Duodenal Biopsies
Completed
22 enrolled
University Hospital, Lille
French National Society of Gastroenterology · collabInstitut National de la Santé Et de la Recherche Médicale, France · collab
NaSingle-groupOpen-labelBasic science
Summary
This study is designed to assess the effect of a new PPARgamma modulator on the expression and activity of the lactase enzyme in human intestinal epithelial cells. Based on their previous experimental results, the investigators hypothesized that modulating intestinal PPARgamma activity is a new pharmacological mechanism allowing the control of lactase expression and activity in the gut
Timeline
- Start
- 2015-07-16
- Primary completion
- 2017-09
- Completion
- 2017-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GED | Small molecule | — | — |