drugset / Trial / NCT02915172

Lenvatinib and Capecitabine in Patients With Advanced Malignancies

NCT02915172

NaSingle-groupOpen-labelTreatment

Summary

There are 2 phases in this study: Phase 1 (dose escalation) and Phase 2 (dose expansion). The goal of Phase 1 of this clinical research study is to find the highest tolerable dose of lenvatinib and Xeloda (capecitabine) that can be given to patients with advanced cancer. The goal of Phase 2 of this study is to learn if the dose of lenvatinib and capecitabine found in Phase 1 can help to control advanced cancer. The safety of this drug combination will be studied in both phases of the study.

Timeline

Start
2016-12
Primary completion
2022-12
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 1000 mg/m2 Oral
Subject Lenvatinib Small molecule 10 mg Oral