drugset / Trial / NCT02915172
Lenvatinib and Capecitabine in Patients With Advanced Malignancies
NaSingle-groupOpen-labelTreatment
Summary
There are 2 phases in this study: Phase 1 (dose escalation) and Phase 2 (dose expansion). The goal of Phase 1 of this clinical research study is to find the highest tolerable dose of lenvatinib and Xeloda (capecitabine) that can be given to patients with advanced cancer. The goal of Phase 2 of this study is to learn if the dose of lenvatinib and capecitabine found in Phase 1 can help to control advanced cancer. The safety of this drug combination will be studied in both phases of the study.
Timeline
- Start
- 2016-12
- Primary completion
- 2022-12
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Capecitabine | Small molecule | 1000 mg/m2 | Oral |
| Subject | Lenvatinib | Small molecule | 10 mg | Oral |
Indications
bone cancer
breast cancer
cancer of unknown primary site
central nervous system cancer
digestive system cancer
female reproductive organ cancer
head and neck cancer
male reproductive organ cancer
malignant endocrine neoplasm
malignant soft tissue neoplasm
malignant urinary system neoplasm
respiratory system cancer