Oral Nitrite for Older Heart Failure With Preserved Ejection Fraction

Summary

This is a randomized double blinded controlled trial of 20-40 mg sodium nitrite tid in subjects with HFpEF. Primary outcomes are measures of physical function with non-invasive and invasive cardiopulmonary exercise testing, and fatigability, skeletal muscle bioenergetics, serology including inflammatory markers and platelet bioenergetics, quality of life measures.

Timeline

Start

2017-04-03

Primary completion

2018-12-02

Completion

2018-12-31

Drugs

Indications