drugset / Trial / NCT02923388
Neuroprotective Effect of Vitamin B12 and Vitamin B6 Against Vincristine Induced Peripheral Neuropathy
RandomizedParallel-groupQuadruple-blindPrevention
Summary
This study will be conducted to evaluate the effect of vitamin B12 and vitamin B6 in delaying the onset and reducing the incidence and severity of Vincristine Induced Peripheral Neuropathy (VIPN) in Acute Lymphoblastic Leukemia (ALL) patient.
Timeline
- Start
- 2016-10
- Primary completion
- 2018-06
- Completion
- 2018-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Pyridoxine | Unknown | 50 mg | Oral |
| Comparator | methylcobalamin | Small molecule | 500 ug | Intravenous |