drugset / Trial / NCT02926586
Fludarabine and Cytarabine Versus High-dose Cytarabine for CBF-AML
Phase 4
Completed
68 enrolled
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of the study is to determine whether Fludarabine in combination with cytarabine is more effective than high-dose cytarabine in post-remission therapy for patients with core-binding factor acute myeloid leukemia
Timeline
- Start
- 2017-01-01
- Primary completion
- 2020-08-16
- Completion
- 2024-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cytarabine | Small molecule | 1500 mg/m2 | Intravenous |
| Comparator | Cytarabine | Small molecule | 2000 mg/m2 | Intravenous |
| Subject | Fludarabine | Small molecule | 30 mg/m2 | Intravenous |
| Subject | Fludarabine | Small molecule | 50 mg/m2 | Intravenous |