drugset / Trial / NCT02929485

Dopaminergic Modulation of Frontostriatal Function With a Dopamine Agonist and COMT Inhibitor

NCT02929485

RandomizedCrossoverTriple-blindBasic science

Summary

In this study, the investigators are looking at how people make decisions about reward-related items, both monetary and food related after taking either the dopamine agonist bromocriptine or the COMT inhibitor tolcapone, in healthy control subjects. Subjects will fill self-report questionnaires and undergo an MRI scan.

Timeline

Start
2013-07
Primary completion
2018-01-31
Completion
2018-01-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Bromocriptine Small molecule 1.25 mg
Subject Tolcapone Unknown 200 mg

Indications