ACTH as A Re-emerging theRapy for Uveitis (The ACTHAR Study)

Summary

The study aims to evaluate the potential role of ACTH gel in the management of non-infectious uveitis.

Timeline

Start

2017-11-10

Primary completion

2020-04-03

Completion

2021-10-28

Publications

• Background Sadiq MA, Agarwal A, Hassan M, Afridi R, Sarwar S, Soliman MK, Do DV, Nguyen QD. Therapies in Development for Non-Infectious Uveitis. Curr Mol Med. 2015;15(6):565-77. doi: 10.2174/1566524015666150731103847.
• Background Montero-Melendez T. ACTH: The forgotten therapy. Semin Immunol. 2015 May;27(3):216-26. doi: 10.1016/j.smim.2015.02.003. Epub 2015 Feb 26.
• Background Durrani OM, Meads CA, Murray PI. Uveitis: a potentially blinding disease. Ophthalmologica. 2004 Jul-Aug;218(4):223-36. doi: 10.1159/000078612.
• Background Lee K, Bajwa A, Freitas-Neto CA, Metzinger JL, Wentworth BA, Foster CS. A comprehensive review and update on the non-biologic treatment of adult noninfectious uveitis: part I. Expert Opin Pharmacother. 2014 Oct;15(15):2141-54. doi: 10.1517/14656566.2014.948417.

Drugs

Indications