drugset / Trial / NCT02931305
Epimedium Prenylflavonoid (EP) Extract for Osteoporosis and Cardiovascular Disease
RandomizedParallel-groupDouble-blindTreatment
Summary
The primary objective of the trial is to develop Epimedium Prenylflavonoid (EP) extract as a pharmaceutical-quality intervention for post-menopausal osteoporosis and cardiovascular disease. There will be 3 cohorts of 10 healthy men each for the Phase 1 study. In each cohort, 8 men will receive the Epimedium capsules and 2 men will received the matched controls.
Timeline
- Start
- 2016-10
- Primary completion
- 2017-01
- Completion
- 2017-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Epimedium Prenylflavonoids Extract | Traditional medicine (herbal / TCM) | 370 mg | Oral |
| Subject | Epimedium Prenylflavonoids Extract | Traditional medicine (herbal / TCM) | 740 mg | Oral |
| Subject | Epimedium Prenylflavonoids Extract | Traditional medicine (herbal / TCM) | 1110 mg | Oral |