drugset / Trial / NCT02931305

Epimedium Prenylflavonoid (EP) Extract for Osteoporosis and Cardiovascular Disease

NCT02931305 ↗

Phase 1 Unknown 30 enrolled National University Hospital, Singapore
RandomizedParallel-groupDouble-blindTreatment

Summary

The primary objective of the trial is to develop Epimedium Prenylflavonoid (EP) extract as a pharmaceutical-quality intervention for post-menopausal osteoporosis and cardiovascular disease. There will be 3 cohorts of 10 healthy men each for the Phase 1 study. In each cohort, 8 men will receive the Epimedium capsules and 2 men will received the matched controls.

Timeline

Start
2016-10
Primary completion
2017-01
Completion
2017-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Epimedium Prenylflavonoids Extract Traditional medicine (herbal / TCM) 370 mg Oral
Subject Epimedium Prenylflavonoids Extract Traditional medicine (herbal / TCM) 740 mg Oral
Subject Epimedium Prenylflavonoids Extract Traditional medicine (herbal / TCM) 1110 mg Oral