drugset / Trial / NCT02933437

The Response To Ajmaline Provocation in Healthy Subjects

NCT02933437

Phase 2 Unknown 100 enrolled St George's, University of London
NaSingle-groupOpen-labelDiagnostic

Summary

Standard, high lead and sodium channel provoked electrocardiograms of a healthy volunteers will be performed to observe the various ECG changes. Participants will the undergo detailed imaging with cardiac magnetic resonance imaging and deep genotyping to identify structural or genetic variants which might dictate the electrocardiographic patterns at rest and with sodium channel provocation.

Timeline

Start
2017-10-22
Primary completion
2019-12
Completion
2019-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Ajmaline Small molecule 1 mg/kg Intravenous