drugset / Trial / NCT02935894

Investigating the Stability, Variability and Mechanism of Incorporation of Lipid Mediators Into Eccrine Sweat

NCT02935894

NaSingle-groupOpen-labelBasic science

Summary

The purpose of this study is to see what the differences are in sweat (amount and small molecule content) collected from different sites of the body and by different methods of sweat stimulation. Additionally, the investigators want to know whether the amount and small molecule content of the sweat is the same in an individual over time, and the same across individuals at a given time. Finally, the investigators want to know how consumption of over-the-counter anti-inflammatory drugs such as ibuprofen will affect the inflammatory mediator content of sweat and how that compares to blood. This information will help to better understand the composition and behavior of sweat and assess its potential utility as a routine clinical tool in skin research.

Timeline

Start
2016-11-28
Primary completion
2017-06-08
Completion
2017-06-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Ibuprofen Small molecule 400 mg
Background Pilocarpine Unknown 5 % Other

Indications

No indication recorded.