drugset / Trial / NCT02942173
CD45RA Depleted T-cell Infusion for Prevention of Infections After TCRab/CD19-depleted Allo-HSCT
Phase 2/3
Completed
150 enrolled
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
RandomizedParallel-groupOpen-labelPrevention
Summary
The purpose of this prospective randomized study is to determine whether infusions of T-memory cells prevent infections in children with leukemia after allogeneic alpha, beta T-cell receptor (TcRab)/CD19-depleted hematopoietic stem cell transplantation (HSCT).
Timeline
- Start
- 2016-10
- Primary completion
- 2019-08-21
- Completion
- 2020-08-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | CD45RA-depleted peripheral blood mononuclear cells | Cell therapy | — | — |