drugset / Trial / NCT02942485
Treatment of Giardia Lamblia Infections in Children
RandomizedParallel-groupOpen-labelTreatment
Summary
This study investigates the efficacy and safety of rectally administered metronidazole for pediatric Giardia lamblia infection, as well as the acceptance of this treatment regimen by patients/caregivers. The investigators hypothesize that rectal metronidazole is non-inferior to single-dose of oral tinidazole and will cure at least 72% of patients, a well as will be tolerated as good as tinidazole.
Timeline
- Start
- 2016-12-01
- Primary completion
- 2019-12-31
- Completion
- 2019-12-31
Outcome
Outcome not reported
Stopped (Enrollment): “Extremely slow enrollment”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metronidazole | Small molecule | 500 mg | Rectal |
| Subject | Metronidazole | Small molecule | 1000 mg | Rectal |
| Subject | Metronidazole | Small molecule | 1500 mg | Rectal |
| Comparator | tinidazole | Small molecule | 50 mg/kg | Oral |