A Second Dose of Measles Vaccine (MV) in the Second Year of Life

Completed 3812 enrolled Bandim Health Project

RandomizedParallel-groupOpen-labelPrevention

Summary

This study evaluates the non-specific effects on child mortality and morbidity of a second dose of measles in the second year of life. Half of the study participants will receive a second dose of measles vaccine at 18 months of age while the other half will receive a second dose of measles by 4 years of age or at the end of the study.

Timeline

Start: 2016-10
Primary completion: 2020-05
Completion: 2021-05

Publications

Background Berendsen MLT, Silva I, Bale C, Nielsen S, Hvidt S, Martins CL, Benn CS, Aaby P. The Effect of a Second Dose of Measles Vaccine at 18 Months of Age on Nonaccidental Deaths and Hospital Admissions in Guinea-Bissau: Interim Analysis of a Randomized Controlled Trial. Clin Infect Dis. 2022 Oct 12;75(8):1370-1378. doi: 10.1093/cid/ciac155.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Measles vaccine	Vaccine	0.5 ml	—

Indications

No indication recorded.