drugset / Trial / NCT02943889

Stem Cell Transplantation in Cirrhotic Patients

NCT02943889 ↗

Phase 1/2 Unknown 40 enrolled Assiut University
Non-randomizedParallel-groupOpen-labelTreatment

Summary

Chronic liver disease end by liver cirrhosis and increases the risk of cancer development. Chronic liver disease in Egypt is recognized as a serious health problem affecting greater than (20 %) of the population, where the main cause is chronic infection. Liver transplantation is still the standard treatment for advanced decompensated liver cirrhosis. However, this treatment is quite limited in clinical practice. Therefore there is a concerted effort around the world to develop regenerative and alternative therapies, so, stem cell-based therapies are emerging as new alternatives to liver transplantation for end-stage liver pathologies.

Timeline

Start
2016-10
Primary completion
2017-06
Completion
2017-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Mesenchymal stem cell transplantation Cell therapy 2e+06 cells/kg Other

Indications