Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients

Summary

Constipation is a known complication of the postoperative period after spinal surgery, where prescription pain medicines called opioids are traditionally used in high doses for the treatment of surgery-related pain. The goal of this study is to determine the effectiveness of Movantik (naloxegol)-a FDA-approved drug used to treat constipation that is caused by opioids-in preventing constipation in patients undergoing spinal fusion surgery at MGH.

Timeline

Start

2017-01

Primary completion

2018-02

Completion

2018-02

Outcome

Outcome not reported

Stopped (Enrollment): “Slow recruitment and inability to extend funding.”

Drugs

Indications