drugset / Trial / NCT02946580
Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients
RandomizedParallel-groupTriple-blindPrevention
Summary
Constipation is a known complication of the postoperative period after spinal surgery, where prescription pain medicines called opioids are traditionally used in high doses for the treatment of surgery-related pain. The goal of this study is to determine the effectiveness of Movantik (naloxegol)-a FDA-approved drug used to treat constipation that is caused by opioids-in preventing constipation in patients undergoing spinal fusion surgery at MGH.
Timeline
- Start
- 2017-01
- Primary completion
- 2018-02
- Completion
- 2018-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naloxegol | Small molecule | 12.5 mg | Oral |
| Subject | Naloxegol | Small molecule | 25 mg | Oral |