drugset / Trial / NCT02953106

Effects of Intranasal Fluticasone Plus Azelastine on Airway Inflammation in Patients With Asthma & Allergic Rhinitis

NCT02953106

Phase 4 Terminated 7 enrolled University of Dundee
RandomizedCrossoverQuadruple-blindTreatment

Summary

Single centre, double-blind, placebo controlled, adaptive design, cross-over trial. The primary objective is to assess the additive effects of using combined intranasal fluticasone propionate plus azelastine nasal spray on airway hyperresponsiveness. This is in patients with persistent asthma and allergic rhinitis, receiving inhaled steroid.

Timeline

Start
2017-01-20
Primary completion
2018-09-10
Completion
2018-09-10

Drugs

EvaluationDrugModalityDoseRoute
Comparator Azelastine Small molecule 137 ug Intranasal
Comparator Fluticasone Other / unclassified 50 ug Intranasal