drugset / Trial / NCT02953106
Effects of Intranasal Fluticasone Plus Azelastine on Airway Inflammation in Patients With Asthma & Allergic Rhinitis
RandomizedCrossoverQuadruple-blindTreatment
Summary
Single centre, double-blind, placebo controlled, adaptive design, cross-over trial. The primary objective is to assess the additive effects of using combined intranasal fluticasone propionate plus azelastine nasal spray on airway hyperresponsiveness. This is in patients with persistent asthma and allergic rhinitis, receiving inhaled steroid.
Timeline
- Start
- 2017-01-20
- Primary completion
- 2018-09-10
- Completion
- 2018-09-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Azelastine | Small molecule | 137 ug | Intranasal |
| Comparator | Fluticasone | Other / unclassified | 50 ug | Intranasal |