drugset / Trial / NCT02953847

The Bioavailability of Rifampicin in (FDCs) Widely Used in South Africa to Treat Drug-susceptible (TB)

NCT02953847

Phase 1 Completed 21 enrolled University of Cape Town
RandomizedCrossoverOpen-labelOther

Summary

3-way cross-over single dose design evaluating bioavailability of 2 rifampicin-containing FDCs vs a single drug comparator in healthy volunteers

Timeline

Start
2016-11
Primary completion
2017-02
Completion
2017-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Rifafour e-275 Unknown 75 mg
Subject Rifafour e-275 Unknown 150 mg
Subject Rifafour e-275 Unknown 275 mg
Subject Rifafour e-275 Unknown 400 mg
Subject Rifampin Small molecule 150 mg
Subject Rimactazid Unknown 75 mg
Subject Rimactazid Unknown 150 mg

Indications