Effect of Furosemide on Confirmation of Ureteral Patency During Routine Cystoscopy

Phase 4 Completed 150 enrolled University of South Florida

RandomizedParallel-groupQuadruple-blindOther

Summary

This study evaluates if administration of IV furosemide leads to expedited confirmation of ureteral patency when compared to placebo (IV saline) in routine cystoscopy performed after urogynecologic surgery.

Timeline

Start: 2017-05-01
Primary completion: 2018-03-31
Completion: 2018-06-30

Outcome

Met primary endpoint

paper intravenous administration of 10 mg furosemide at time of intraoperative cystoscopy resulted in a statistically significantly shorter time to confirmation of ureteral patency PMID 30870291 ↗

Publications

Patton S, Tanner JP, Prieto I, Jackson E, Greene K, Bassaly R, Wyman AM. Furosemide Use and Time to Confirmation of Ureteral Patency During Intraoperative Cystoscopy: A Randomized Controlled Trial. Obstet Gynecol. 2019 Apr;133(4):669-674. doi: 10.1097/AOG.0000000000003155.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Furosemide	Other / unclassified	10 mg	Intravenous

Indications

No indication recorded.