drugset / Trial / NCT02965859
The Safety and Dose-range Study of Metacavir Enteric-coated Capsules in Patients With Chronic Hepatitis B
RandomizedParallel-groupDouble-blindTreatment
Summary
The study objective is to evaluate the safety and effectiveness of different doses of Metacavir Enteric-coated Capsules in treatment of chronic hepatitis B,as well as to find an appropriate clinical dosage by comparing the effect of different doses of treatment,in order to provide references of clinical trial of the next phase.
Timeline
- Start
- 2012-12
- Primary completion
- 2018-12
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Adefovir dipivoxil | Small molecule | 10 mg | — |
| Subject | Metacavir | Small molecule | 80 mg | — |
| Subject | Metacavir | Small molecule | 160 mg | — |
| Subject | Metacavir | Small molecule | 320 mg | — |