drugset / Trial / NCT02982902

T Cell Therapy of Opportunistic Cytomegalovirus Infection

NCT02982902

Phase 0 Recruiting 20 enrolled Mari Dallas
NaSingle-groupOpen-labelSupportive care

Summary

The purpose of this study is to determine if a specific type of cell-based immunotherapy, using T-cells from a donor that are specific against cytomegalovirus (CMV) is feasible to treat infections by CMV. Adoptive T-cell therapy is an investigational (experimental) therapy that works by using the blood of a donor and selecting the T-cells that can respond against a specific infectious entity. These selected T-cells are then infused to the patient, to try to give the immune system the ability to fight the infection. Adoptive T-cell therapy is experimental because it is not approved by the Food and Drug Administration (FDA).

Timeline

Start
2020-05-27
Primary completion
2027-08
Completion
2028-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Pembrolizumab Monoclonal antibody Other