drugset / Trial / NCT02984397

Chronic Widespread Pain and White Blood Cell Activation

NCT02984397

RandomizedParallel-groupTriple-blindTreatment

Summary

Our goal is to conduct a proof-of-concept trial to test the efficacy of KF treatment in adolescents with severe CWP not responding to the standard of care (SOC) treatment program in a multidisciplinary tertiary care chronic pain clinic. The changes associated to the interventions (KF or placebo) will be quantified using the Patients' Global Impression of Change (PGIC) scale after 16 weeks of treatment. Secondary, we aim to evaluate the effects of KF on the pain sensitivity, physical and emotional functioning, and we will also explore the potential biological underlying mechanisms.

Timeline

Start
2016-12
Primary completion
2020-01
Completion
2020-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Ketotifen Small molecule 3 mg

Indications