drugset / Trial / NCT02985372
Decitabine in Combination With Low-dose Cytarabine in Elderly Patients With Acute Myeloid Leukemia
Phase 3
Unknown
30 enrolled
Chunyan Ji
Binzhou Medical University · collabCentral Hospital of Zibo · collabHeze Municipal Hospital · collabJinan Central Hospital · collabJinan Military Genaral Hospital · collabJining Medical University · collabLinyi People's Hospital · collabQianfoshan Hospital · collabQilu Hospital of Shandong University (Qingdao) · collabQingdao University · collabRizhao People's Hospital · collabShengli Oilfield Hospital · collabTaian City Central Hospital · collabTaishan Medical University Affiliated Hospital · collabWeifang Medical University · collabWeihai Municipal Hospital · collabZibo First Hospital · collab
NaSingle-groupOpen-labelTreatment
Summary
This prospective multicenter clinical study was designed to assess the efficacy and safety of decitabine in combination with low-dose cytarabine induction treatment for elderly patients with newly diagnosed acute myeloid leukemia (AML).
Timeline
- Start
- 2016-12
- Primary completion
- 2018-12
- Completion
- 2019-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cytarabine | Small molecule | 1000 mg/m2 | Intravenous |
| Subject | Decitabine | Small molecule | 15 mg/m2 | Intravenous |