A Dose-ranging Study of Orvepitant in Patients With Chronic Refractory Cough

Summary

The purpose of this study is to determine the effectiveness of three doses of orvepitant, taken once a day, in the treatment of chronic refractory cough.

Timeline

Start

2017-05-22

Primary completion

2019-01-14

Completion

2019-01-24

Outcome

Missed primary endpoint

registry analysis (superiority test); Orvepitant 10mg vs Placebo; p = 0.324 NCT02993822 ↗

registry analysis (superiority test); Orvepitant 20mg vs Placebo; p = 0.332 NCT02993822 ↗

registry analysis (superiority test); Orvepitant 30mg vs Placebo; p = 0.531 NCT02993822 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Orvepitant	Small molecule	10 mg	Oral
Subject	Orvepitant	Small molecule	20 mg	Oral
Subject	Orvepitant	Small molecule	30 mg	Oral

Indications

No indication recorded.