drugset / Trial / NCT02994173
Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients
Phase 4
Completed
100 enrolled
Turku University Hospital
University of Helsinki · collabUniversity of Turku · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
To study the multimodal protocol combining adjunct ketamine with oxycodone in intravenous patient-controlled analgesia bolus dosing and effects in patients scheduled for posterolateral lumbar spine fusion with bilateral transpedicular screw instrumentation
Timeline
- Start
- 2017-02-01
- Primary completion
- 2019-11-03
- Completion
- 2019-12-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Esketamine | Other / unclassified | 0.25 mg/ml | Intravenous |
| Comparator | Esketamine | Other / unclassified | 0.5 mg/ml | Intravenous |
| Comparator | Esketamine | Other / unclassified | 0.75 mg/ml | Intravenous |
| Comparator | Oxycodone | Other / unclassified | 1 mg/ml | Intravenous |
Indications
No indication recorded.