drugset / Trial / NCT02994251

A Trial of Systemic Chemotherapy in Combination With Conventional Transarterial Chemoembolization in Patients With Advanced Intra-Hepatic Cholangiocarcinoma

NCT02994251

Phase 2 Terminated 1 enrolled Yale University
NaSingle-groupOpen-labelTreatment

Summary

The study will be a single-center, single-arm, Phase II study of gemcitabine and cisplatin in combination with conventional trans-arterial chemoembolization therapy in adult patients with advanced ICC. 25 patients will be enrolled over the course of 2 years, with an additional 1.5 years for patient follow-up.

Timeline

Start
2017-06-21
Primary completion
2018-11-06
Completion
2018-11-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Cisplatin Other / unclassified 25 mg/m2 Intravenous
Subject Doxorubicin Other / unclassified Other
Subject Gemcitabine Small molecule 1000 mg/m2 Intravenous
Subject Mitomycin C Other / unclassified Other