drugset / Trial / NCT02995512

Mechanistic Effects of Colchicine in Patients With Myocardial Infarction

NCT02995512

Phase 4 Withdrawn NYU Langone Health
NaSingle-groupOpen-labelTreatment

Summary

The aim of this study is to determine the immuno-modulatory mechanistic effects of colchicine in patients with myocardial infarction (MI). Investigators hypothesize that colchicine exerts its anti-inflammatory properties by switching the metabolism of neutrophils, thereby reducing the expression of adhesion molecules responsible for their recruitment in MI.

Timeline

Start
2017-05-01
Primary completion
2018-09-12
Completion
2018-09-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Colchicine Small molecule 0.6 mg Oral

Indications