Acute Effect of Agiotensin-(1-7) in Healthy and Hypertensive Subjects

Summary

In the modern concept of Renin-angiotensin System, Angiotensin-(1-7) plays a key role and demonstrates promising therapeutic potential due to it is generally opposite effects to Angiotensin II. The aim is to evaluate the effect of Ang-(1-7) acute administration on systolic and diastolic blood pressure (SBP and DBP) and heart rate (HR) in healthy and hypertensive subjects.

Timeline

Start

2014-01

Primary completion

2017-02

Completion

2017-03

Drugs

Indications